RSC Adv. 2023 Mar 7;13(11):7432-7435. doi: 10.1039/d2ra08257h. eCollection 2023 Mar 1.
Asymmetric ring-opening reactions of donor-acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93% yields with 79% to 99% enantiomeric excesses.
PMID:36895764 | PMC:PMC9990749 | DOI:10.1039/d2ra08257h