Synthesis of a chitosan nanoparticle suspension and its protective effects against enamel demineralization after an in vitro cariogenic challenge

J Appl Oral Sci. 2021 Oct 8;29:e20210120. doi: 10.1590/1678-7757-2021-0120. eCollection 2021. ABSTRACT OBJECTIVE: Our study aims to synthesize, characterize, and determine the effects of a ChNPs suspension on human enamel… Read more

Development of Amino Acids Functionalized SBA-15 for the Improvement of Protein Adsorption

Molecules. 2021 Oct 8;26(19):6085. doi: 10.3390/molecules26196085. ABSTRACT Ordered mesoporous materials and their modification with multiple functional groups are of wide scientific interest for many applications involving interaction with biological systems… Read more

Patient-Derived Tumor Chemosensitization of GKB202, an Antrodia Cinnamomea Mycelium-Derived Bioactive Compound

Molecules. 2021 Oct 4;26(19):6018. doi: 10.3390/molecules26196018. ABSTRACT Oral cancers, hepatocellular carcinoma, and colorectal cancers are the three most common cancers, leading to 18,000 cases of cancer-related mortality in Taiwan per… Read more

Development of Antibacterial, Degradable and pH-Responsive Chitosan/Guar Gum/Polyvinyl Alcohol Blended Hydrogels for Wound Dressing

Molecules. 2021 Sep 30;26(19):5937. doi: 10.3390/molecules26195937. ABSTRACT The present research is based on the fabrication preparation of CS/PVA/GG blended hydrogel with nontoxic tetra orthosilicate (TEOS) for sustained paracetamol release. Different… Read more

Thiol-Responsive Gold Nanodot Swarm with Glycol Chitosan for Photothermal Cancer Therapy

Molecules. 2021 Oct 2;26(19):5980. doi: 10.3390/molecules26195980. ABSTRACT Photothermal therapy (PTT) is one of the most promising cancer treatment methods because hyperthermal effects and immunogenic cell death via PTT are destructive… Read more

Amyloids as Building Blocks for Macroscopic Functional Materials: Designs, Applications and Challenges

Int J Mol Sci. 2021 Oct 2;22(19):10698. doi: 10.3390/ijms221910698. ABSTRACT Amyloids are self-assembled protein aggregates that take cross-β fibrillar morphology. Although some amyloid proteins are best known for their association… Read more

Shining light on chiral inorganic nanomaterials for biological issues

Theranostics. 2021 Sep 7;11(19):9262-9295. doi: 10.7150/thno.64511. eCollection 2021. ABSTRACT The rapid development of chiral inorganic nanostructures has greatly expanded from intrinsically chiral nanoparticles to more sophisticated assemblies made by organics,… Read more

Polyamino acid calcified nanohybrids induce immunogenic cell death for augmented chemotherapy and chemo-photodynamic synergistic therapy

Theranostics. 2021 Sep 21;11(19):9652-9666. doi: 10.7150/thno.64354. eCollection 2021. ABSTRACT Background: Monotherapy for cancer treatment is limited by unstable efficacy and uncontrollable toxic side effects, while the multifunctional nanoplatform with complex… Read more

Global Rhes knockout in the Q175 Huntington’s disease mouse model

PLoS One. 2021 Oct 14;16(10):e0258486. doi: 10.1371/journal.pone.0258486. eCollection 2021. ABSTRACT Huntington’s disease (HD) results from an expansion mutation in the polyglutamine tract in huntingtin. Although huntingtin is ubiquitously expressed in… Read more

Construction and Validation of an Immune Cell Signature Score to Evaluate Prognosis and Therapeutic Efficacy in Hepatocellular Carcinoma

Front Genet. 2021 Sep 27;12:741226. doi: 10.3389/fgene.2021.741226. eCollection 2021. ABSTRACT Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy with high morbidity and mortality worldwide. Tumor immune microenvironment… Read more