ACS Omega. 2022 Dec 7;7(50):46174-46182. doi: 10.1021/acsomega.2c04299. eCollection 2022 Dec 20.

ABSTRACT

Herein, we report practical Cu(BF4)2/activated carbon-catalyzed amination of various anilines, isoquinolinone, and naphthyridinone with aryl boronic acids. The ultrasonic and rotary evaporation treatment of the mixture of aq. Cu(BF4)2 and activated carbon in methanol afforded a novel Cu(II)-catalyst, which is air-stable and can be effectively applied in the Chan-Lam coupling reaction. The products of N-arylation were isolated in good to excellent yields at low catalytic loading. And Cu(BF4)2/AC also showed good reusability.

PMID:36570313 | PMC:PMC9773803 | DOI:10.1021/acsomega.2c04299