Cu(i)-catalyzed cross-coupling of primary amines with 2,2′-dibromo-1,1′-biphenyl for the synthesis of polysubstituted carbazole

RSC Adv. 2022 Aug 25;12(37):24232-24236. doi: 10.1039/d2ra03323b. eCollection 2022 Aug 22.

ABSTRACT

A Cu(i)-catalyzed cross-coupling of primary amines with 2,2′-dibromo-1,1′-biphenyl for the synthesis of polysubstituted carbazole has been achieved. This protocol provides an efficient strategy for the synthesis of carbazole using cheap copper catalysts with diamine ligand, and it provides convenient access to a series of carbazole derivatives in moderate yields.

PMID:36128530 | PMC:PMC9404109 | DOI:10.1039/d2ra03323b

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