Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike

Future Virol. 2023 Feb:10.2217/fvl-2022-0181. doi: 10.2217/fvl-2022-0181. Epub 2023 Mar 6.


The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.

PMID:36896145 | PMC:PMC9987531 | DOI:10.2217/fvl-2022-0181


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